Creating 100% Pathogen Free Environments

March 16, 2010 — Giant Step Forward for AsepticSure™

Medizone International Announces Giant Step Forward for AsepticSure™

San Francisco, March 16, 2010 Medizone International, Inc., (MZEI.OB) announces a giant step forward for the AsepticSure™ hospital sterilization system. Edwin Marshall, Medizone’s Chief Executive Officer explained, “A week ago we announced completing the first full round of room scale trials eliminating all pathogens across the ‘Super Bug’ spectrum on stainless steel surfaces. While it may seem counterintuitive, stainless is one of the more difficult surfaces to fully sterilize when contaminated with these highly resistant bacteria. Stainless also represents an FDA standard test surface. Today, we are announcing further developments that should have tremendous commercial implications relative to hospital acceptance of AsepticSure™ as the new standard in providing greatly enhanced patient safety.

Test results from our second stage of ‘room scale’ trials have clearly demonstrated that AsepticSure™ can reliably achieve 6 log (99.9999%) kill or greater on Porcelain and Formica as well as stainless surfaces. These materials represent the majority of all hospital surfaces. Utilizing a unique additional technology that is protected under our original patent filing of July 13, 2009, we have also demonstrated 6 log reductions with many common fabrics. Thus, it now appears the AsepticSure™ system is capable of decontamination to the previously unobtainable 6 log standard on all hospital surfaces, hard or soft.

Of commercial significance in a hospital setting, we are now able to greatly reduce the time required to achieve 6 log kills on hard surfaces to 30 minutes of exposure. With the charge time and destruct time for reuse of the space factored in, that translates to a room turn around time of 80 minutes, a 40 minute saving in total turn around time from our original target of 2 hours. Fabric exposure requires an additional 15 minutes to achieve the same 6 log kill rate, which represents a full turn around for a thorough cleaning of about 95 minutes for all surface materials.”

“This reduction in room turn around time from 120 minutes to 95 minutes for a thorough sterilization will be viewed very favorably by hospitals,” stated Dr. Michael Shannon, Medizone’s Director of Medical Affairs, who continued, “Any significant reduction in treatment time to put a room back into service is critical to hospital flow patterns. Given the sum of our results, it now appears that a typical protocol might have a hospital perform a first cleaning of 95 minutes to fully sterilize the space, which would be followed by cleanings, perhaps as infrequently as one time per week for lower risk settings, requiring only 80 minutes to complete. Not only is AsepticSure™ continuing to demonstrate its superlative antimicrobial efficacy, it is increasingly becoming apparent that it will be viewed as a practical necessity easily managed by trained hospital maintenance staff without putting rooms out of service for unacceptable periods of time.”

Medizone International, Inc., is a research and development company engaged in developing its AsepticSure™ System to decontaminate and sterilize hospitals, sports training facilities, schools and other critical infrastructure. A government variant is being developed for bio-terrorism counter measures. Successful decontamination by AsepticSure™ to the 6 log standard or greater has been demonstrated with C.difficile, E coli, Pseudomonas aeruginous, MRSA, VRE and Bacillius subtilis.

This Press Release contains certain forward looking statements that involve substantial risks and uncertainties, including, but not limited to, the results of ongoing clinical studies, economic conditions, product and technology development, production efficiencies, product demand, competitive products, competitive environment, successful testing and government regulatory issues. Additional risks are identified in the company's filings made with the Securities and Exchange Commission.

Investor Relations: 415-868-0300

E-mail: operations@medizoneint.com

Contact:

Medizone International, Inc. (MZEI.OB)

4000 Bridgeway, Suite 401,
Sausalito, CA 94965

Telephone: 415-331-0303

Email
: operations@medizoneint.com

Investor Relations:

John Pentony

Investor Relations,
Medizone International, Inc.

Telephone: (415) 331-0202

E: j.pentony@medizoneint.com

Media Contact:

Gary Hanauer

Media Relations,
Medizone International, Inc.

Telephone: (510) 686-1238

E: GarHan@aol.com