Creating 100% Pathogen Free Environments

Sept. 26, 2008 – Medizone International Appoints Equiti-trends Advisors as Shareholder Relations Firm

Medizone International, Inc. (MZEI.PK) Appoints Equiti-trends Advisors as Shareholder Relations Firm

SAN FRANCISCO,CALIFORNIA. September 26, 2008 - Medizone International, Inc. (Pink Sheets: MZEI) is pleased to announce that effective immediately Equiti-trend Advisors LLC has been retained as the company's investor communications and shareholder relations firm. A San Diego-based firm, Equiti-trend specializes in developing long-term, investor communications and market awareness programs for emerging growth companies based in the U.S. and Canada.

Mr. Edwin Marshall, Chairman and CEO of Medizone International, commented: "After the uninspiring market response to our recent announcement regarding the appointment of Dr. Michael E. Shannon to our Board of Directors, the Company has decided to significantly enhance our investor communications and awareness efforts. I consider Dr. Shannon, the former Director General of the Canadian Laboratory Centre for Disease Control, to be the finest, brightest and most capable medical researcher and project director imaginable. His contributions to Medizone as the Company moves towards commercialization will be immeasurable. In the future, we want to make sure the investment community is aware of the great strides forward Medizone is making. After meeting with the principles of Equiti-trend, and their team of market and communication representatives, I am confident that their firm is fundamentally designed to meet our needs, and that Medizone will benefit measurably from their services. "

“We are extremely pleased to be aligning with Medizone during this exciting and important period of the Company’s development,” commented Larry Downs, director of communications for Equiti-trend. “Our planned program will include a multi-faceted approach to garnering a new, much larger investor audience, developing and maintaining strong shareholder communications, and assisting the Company in telling its tremendous story to investors from all walks in a manner that is clear and consistent.”

Equiti-trend’s corporate communications programs include outbound telephone activities to potential new investors that comprise their proprietary investor database, ongoing communications with current shareholders via postcard mailers and their toll-free investor line, placement of clients’ stories within a series of partnered investment-oriented Websites and newsletters, and enhanced distribution of corporate news releases to investment and consumer based Web portals and traditional print channels, in the U.S. and worldwide.

Medizone International, Inc., is a research and development stage company engaged in the development of patented and unpatented technologies and protocols for O3 based bio-oxidative treatment of diseases caused by lipid enveloped viruses, including Acquired Immune Deficiency Syndrome (AIDS), Hepatitis B & C, and Herpes, the decontamination of blood, blood products and veterinarian serum products, and the treatment of external pathogenic conditions.

This Press Release contains certain forward looking statements that involve substantial risks and uncertainties, including, but not limited to, the results of ongoing clinical studies, economic conditions, product and technology development, production efficiencies, product demand, competitive products, competitive environment, successful testing and government regulatory issues. Additional risks are identified in the company's filings made with the Securities and Exchange Commission.

Contact:

Medizone International, Inc. (MZEI.OB)

4000 Bridgeway, Suite 401,
Sausalito, CA 94965

Telephone: 415-331-0303

Email
: operations@medizoneint.com

Investor Relations:

John Pentony

Investor Relations,
Medizone International, Inc.

Telephone: (415) 331-0202

E: j.pentony@medizoneint.com

Media Contact:

Gary Hanauer

Media Relations,
Medizone International, Inc.

Telephone: (510) 686-1238

E: GarHan@aol.com